Description of service

PHE will provide access to the ferret model of influenza at BSL2 as part of TNA8 Animal models platform.

Timeline 

12 weeks, maximum study duration

3-4 months of advance notice required before start of study

Contact 

Anthony Marriott

anthony.marriott@phe.gov.uk

00441980 612371

Services do NOT include

Optional: additional groups of ferrets for lung/tissues; virus neutralisation titres; histopathology; immunogenicity studies.

Possible Output

Report detailing clinical parameters of disease, virology (nasal wash virus titres), serology, IFN-gamma ELISA, IFN-gamma Elispot.

Sample Requirements - input of users

User to provide vaccine samples of suitable purity and quality for vaccination of ferrets. Documentation should be provided confirming quality control (freedom from pyrogens, freedom from bacterial contamination). User to provide antigen for immunological assays if require

Lead Scientist

Anthony Marriott

Related services

Users may wish to use analytics services to assess purity of vaccine candidates (TNA3).

Immunogenicity and chanllenge studies in ferrets

Paid Service