You are cordially invited to a webinar "Structural vaccinology approach: the exploitation of the structure knowledge for the rational vaccine design/optimization" presented by prof. Lucia Banci (INSTRUCT ERIC).
The comprehension of the recognition pattern and mode of interaction between antigen and antibody is an essential aspect for vaccine rational design and optimisation. To reach this goal structural characterisation is necessary as it would provide a detailed description of the conformational properties of the epitopes and of their interaction patterns with antibodies. A few examples of the application of the presented approach, i.e. Structural Vaccinology, for the optimisation of vaccines will be presented. The second part will be a Q&A session during which related questions will be answered (Open forum for questions ).
The webinar will take place on Wednesday, 10 April 2019 at 16:00 CET. If you would like to attend, please send an e-mail to firstname.lastname@example.org and we will send you meeting details in due course.
Due to the fact that there are limited places available and participation will be on a “first come first served basis”, registration will close when maximum number of participantswill be reached.
Lucia Banci (Professor of Chemistry at the University of Florence) - recognised as a world class leader in the characterisation of functional processes in a cellular context with atomic resolution. Her work integrates structural, interaction and dynamical information with thermodynamic properties, particularly in metal ion trafficking in the cell. Her most recent work uses an innovative NMR approach that detects single proteins and their transitions at atomic resolution and in the live cell environment, thereby realising the bridge between cellular studies and structural characterisation.
Professor Banci’s knowledge of structural biology approaches using NMR also led to an innovative approach to vaccine design which was an essential contribution to the development of a vaccine against meningococcus B pathogen. Her structural characterisation of pathogen variants led to the design of a chimeric vaccine antigen that affords complete protection against all variants of meningococcus B.
The Webminar is now available here.